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Hideyuki Akaza Selected Research

acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamide

7/2021Primary Androgen-Depletion Therapy Prevails Not Only for Metastatic but Also for Nonmetastatic Hormone-Naïve Prostate Cancer in Japan-Recent Trends and Efficacy.
6/2018Efficacy and safety of 3-month dosing regimen of degarelix in Japanese subjects with prostate cancer: A phase III study.
5/2017Efficacy and safety of a 3-month dosing regimen of degarelix in Japanese patients with prostate cancer: a phase II maintenance-dose-finding study.
6/2012The efficacy and safety of degarelix, a GnRH antagonist: a 12-month, multicentre, randomized, maintenance dose-finding phase II study in Japanese patients with prostate cancer.

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Hideyuki Akaza Research Topics

Disease

115Prostatic Neoplasms (Prostate Cancer)
02/2022 - 05/2002
70Neoplasms (Cancer)
09/2021 - 01/2002
55Renal Cell Carcinoma (Grawitz Tumor)
08/2020 - 08/2002
31Urinary Bladder Neoplasms (Bladder Cancer)
01/2019 - 01/2002
19Neoplasm Metastasis (Metastasis)
09/2013 - 01/2002
13Testicular Neoplasms (Testicular Cancer)
04/2012 - 05/2002
8Disease Progression
01/2022 - 08/2002
8Carcinogenesis
06/2011 - 05/2002
8Transitional Cell Carcinoma
03/2008 - 08/2003
7Non-Muscle Invasive Bladder Neoplasms
08/2013 - 02/2009
6Drug-Related Side Effects and Adverse Reactions
10/2015 - 05/2004
6Hypertension (High Blood Pressure)
10/2015 - 06/2009
6Carcinoma (Carcinomatosis)
06/2011 - 03/2003
6Urologic Neoplasms (Urological Cancer)
02/2009 - 01/2002
5Infections
10/2019 - 04/2006
5Fatigue
03/2015 - 06/2009
4Stomatitis
10/2019 - 01/2011
4Exanthema (Rash)
10/2015 - 10/2007
4Diarrhea
02/2014 - 10/2007
4Hand-Foot Syndrome
06/2013 - 03/2010
4Pain (Aches)
11/2012 - 05/2004
4Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
01/2011 - 03/2003
3Kidney Neoplasms (Kidney Cancer)
01/2018 - 11/2010
3Carcinoma in Situ
01/2016 - 04/2006
3Pneumonia (Pneumonitis)
01/2011 - 07/2006
3Testicular Germ Cell Tumor
01/2011 - 01/2007
3Residual Neoplasm
04/2006 - 03/2003
2Cardiovascular Diseases (Cardiovascular Disease)
01/2020 - 05/2012

Drug/Important Bio-Agent (IBA)

52AndrogensIBA
01/2022 - 06/2003
26Hormones (Hormone)IBA
07/2021 - 11/2002
20Prostate-Specific Antigen (Semenogelase)IBA
01/2022 - 03/2004
16Gonadotropin-Releasing Hormone (GnRH)FDA Link
07/2021 - 08/2002
13IsoflavonesIBA
09/2016 - 08/2002
12Sorafenib (BAY 43-9006)FDA Link
01/2020 - 10/2007
11Docetaxel (Taxotere)FDA Link
08/2021 - 03/2004
11Cisplatin (Platino)FDA LinkGeneric
12/2010 - 01/2002
10CytokinesIBA
12/2014 - 04/2006
10Interferon-alpha (Interferon Alfa)IBA
07/2010 - 12/2004
9EquolIBA
09/2016 - 08/2002
9Pharmaceutical PreparationsIBA
02/2014 - 12/2002
7Leuprolide (Lupron)FDA LinkGeneric
07/2021 - 05/2004
6Androgen Antagonists (Antiandrogens)IBA
02/2022 - 01/2006
6Axitinib (AG 013736)IBA
09/2017 - 11/2011
6daidzeinIBA
09/2016 - 08/2002
6Biomarkers (Surrogate Marker)IBA
06/2015 - 10/2003
6bicalutamide (Casodex)FDA LinkGeneric
07/2013 - 01/2004
6Interleukin-2 (IL2)IBA
08/2011 - 01/2002
6Messenger RNA (mRNA)IBA
12/2010 - 10/2003
5Lipase (Acid Lipase)FDA Link
10/2015 - 10/2007
5Sunitinib (Sutent)FDA Link
06/2015 - 06/2009
5Prednisolone (Predate)FDA LinkGeneric
02/2015 - 01/2004
5EnzymesIBA
11/2012 - 04/2006
5alpha-Fetoproteins (alpha-Fetoprotein)IBA
03/2005 - 10/2003
4acetyl- 2- naphthylalanyl- 3- chlorophenylalanyl- 1- oxohexadecyl- seryl- 4- aminophenylalanyl(hydroorotyl)- 4- aminophenylalanyl(carbamoyl)- leucyl- ILys- prolyl- alaninamideFDA Link
07/2021 - 06/2012
4EverolimusFDA Link
10/2019 - 08/2010
4Liposomes (Liposome)IBA
01/2019 - 03/2009
4Cell Wall SkeletonIBA
02/2014 - 10/2010
4Etoposide (VP 16)FDA LinkGeneric
12/2010 - 07/2006
4Bleomycin (Blenoxane)FDA LinkGeneric
12/2010 - 11/2003
4nuclear matrix protein 22IBA
03/2008 - 12/2003
4Methotrexate (Mexate)FDA LinkGeneric
03/2007 - 01/2002
4Tumor Biomarkers (Tumor Markers)IBA
07/2004 - 05/2002
3Chlormadinone Acetate (Chlormadinone)IBA
02/2022 - 05/2004
3Androgen Receptors (Androgen Receptor)IBA
06/2021 - 05/2012
3Testosterone (Sustanon)FDA Link
01/2020 - 06/2012
3Tyrosine Kinase InhibitorsIBA
01/2018 - 03/2006
3Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
06/2017 - 11/2011
3GenisteinIBA
09/2016 - 08/2002
3AmylasesFDA Link
10/2015 - 10/2007
3Abiraterone AcetateIBA
12/2014 - 10/2014
3InterferonsIBA
02/2013 - 11/2010
3Phosphotransferases (Kinase)IBA
11/2012 - 10/2007
3Proteins (Proteins, Gene)FDA Link
11/2011 - 04/2006
3Formaldehyde (Formol)FDA Link
01/2011 - 03/2006
3SteroidsIBA
01/2011 - 01/2004
3Chorionic Gonadotropin (Human Chorionic Gonadotropin)FDA LinkGeneric
12/2010 - 10/2003
3Antineoplastic Agents (Antineoplastics)IBA
11/2010 - 04/2003
3Doxorubicin (Adriamycin)FDA LinkGeneric
03/2007 - 01/2002
3K cadherinIBA
05/2006 - 10/2003
2enzalutamideIBA
08/2021 - 08/2016
2Goserelin (Zoladex)FDA Link
07/2021 - 06/2018
2temsirolimusFDA Link
08/2020 - 09/2012
2relugolixIBA
01/2020 - 10/2019
2Therapeutic UsesIBA
01/2020 - 06/2011

Therapy/Procedure

114Therapeutics
01/2022 - 01/2002
30Drug Therapy (Chemotherapy)
08/2021 - 01/2002
29Castration
01/2022 - 04/2008
8Prostatectomy (Retropubic Prostatectomy)
03/2018 - 12/2003
8Radiotherapy
01/2015 - 05/2002
6Immunotherapy
01/2019 - 01/2004
6Chemoprevention
07/2013 - 01/2002
6Nephrectomy
02/2013 - 09/2004
4Drug Tapering
04/2013 - 01/2011
4Intravesical Administration
09/2010 - 01/2002
4Induction Chemotherapy
07/2006 - 03/2003
3Transurethral Resection of Bladder
12/2018 - 04/2006
3Intramuscular Injections
05/2014 - 04/2009
3Aftercare (After-Treatment)
09/2012 - 05/2004
3Lasers (Laser)
11/2010 - 06/2007
3Combination Drug Therapy (Combination Chemotherapy)
02/2009 - 08/2003